Ромлусевимаб
RomlusevimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2509447-08-7
Химическое название
immunoglobulin G1-lambda2, anti-[severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein, receptor binding domain (RBD)], Homo sapiens monoclonal antibody;
gamma1 heavy chain Homo sapiens (1-449) [VH (Homo sapiens IGHV7-4-1*02 (95.9%) -(IGHD) -IGHJ6*01 (100%), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*01, G1m17,1, G1v21 CH2 Y15.1, T16, E18 (CH1 K120 (216) (120-217), hinge 1-15 (218-232), CH2 M15.1>Y (254), S16>T (256), T18>E (258) (233-342), CH3 D12 (358), L14 (360) (343-447), CHS (448-449)) (120-449)], (222-213')-disulfide with lambda2 light chain Homo sapiens (1'-214') [V-LAMBDA (Homo sapiens IGLV3-21*01 (97.9%) -IGLJ2*01 (100%), CDR-IMGT [6.3.11] (26-31.49-51.88-98)) (1'-108') -Homo sapiens IGLC2*01 (100%) (109'-214')]; dimer (228-228''
gamma1 heavy chain Homo sapiens (1-449) [VH (Homo sapiens IGHV7-4-1*02 (95.9%) -(IGHD) -IGHJ6*01 (100%), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*01, G1m17,1, G1v21 CH2 Y15.1, T16, E18 (CH1 K120 (216) (120-217), hinge 1-15 (218-232), CH2 M15.1>Y (254), S16>T (256), T18>E (258) (233-342), CH3 D12 (358), L14 (360) (343-447), CHS (448-449)) (120-449)], (222-213')-disulfide with lambda2 light chain Homo sapiens (1'-214') [V-LAMBDA (Homo sapiens IGLV3-21*01 (97.9%) -IGLJ2*01 (100%), CDR-IMGT [6.3.11] (26-31.49-51.88-98)) (1'-108') -Homo sapiens IGLC2*01 (100%) (109'-214')]; dimer (228-228''
Структура
Иностранные названия
- Romlusevimabum (латинское)
- Romlusevimab (английское)
- Romlusevimab (немецкое)
- Romlusévimab (французское)
- Romlusevimab (испанское)
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