Руксорубарт

Prop. INN (наименование, предложенное ВОЗ)

2842046-67-5

immunoglobulin G1-kappa, anti-[Homo sapiens CFB (complement factor B, B-factor properdin, properdin factor B, properdin B, BFD, BF)];
H-gamma1 heavy chain (1-451) [VH Musmus/Homsap (Mus musculus IGHV1-7*02 (90.8%) -(IGHD) -IGHJ4*01 (93.3%) S123>L (116)/Homo sapiens IGHV1-46*01 (74.5%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.14] (26-33.51-58.97-110)) (1-121) -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, CH3 D12, L14, G1v29 CH2 A84.4 (CH1 K120 (218) (122-219), hinge 1-15 (220-234), CH2 N84.4>A (301) (235-344), CH3 D12 (360), L14 (362) (345-449), CHS (450-451)) (122-451)], (224-214')-disulfide with L-kappa light chain (1'-214') [V-KAPPA Musmus/Homsap (Mus musculus IGKV16-104*01 (90.6%) -IGKJ2*03 (90.9%) S120>Q (100')/Homo sapiens IGKV1-9*01 (78.9%) -IGKJ2*02 (100%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')]; dimer (230-230'':233-233'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, non-glycosylated

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