Сабирнетуг

Rec. INN (наименование, зарегистрированное ВОЗ)

2747959-38-0

immunoglobulin G2-kappa, anti-[Homo sapiens (amyloid beta A4 precursor protein) Abeta42 and Abeta40 soluble non-fibrillar oligomers], humanized monoclonal antibody;
gamma2 heavy chain humanized (1-443) [VH (Homo sapiens IGHV3-48*01 (92.9%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.10] (26-33.51-58.97-106)) (1-117) -Homo sapiens IGHG2*01, G2m.. CH2 V45.1 (CH1 (118-215), hinge 1-12 (216-227), CH2 V45.1 (278) (228-336), CH3 (337-441), CHS (442-443)) (118-443)], (131-219')-disulfide with kappa light chain humanized (1'-219') [V-KAPPA (Homo sapiens IGKV2-28*01 (89.5%) -IGKJ2*03 (100%), CDR-IMGT [11.3.9] (27-37.55-57.94-102)) (1'-112') -Homo sapiens IGKC*01, Km3 A45.1 (158), V101 (196) (113'-219')]; dimer (219-219'':220-220'':223-223'':226-226'')-tetrakisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa

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