Сацитузумаб
SacituzumabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
Химическое название
immunoglobulin G1-kappa, anti-[Homo sapiens TACSTD2 (tumor-associated calcium signal transducer 2, membrane component chromosome 1 surface marker 1, M1S1, gastrointestinal tumor-associated antigen GA7331, pancreatic carcinoma marker protein GA733-1, epithelial glycoprotein-1, EGP-1, trophoblast antigen-2, cell surface glycoprotein Trop-2, TROP2)], humanized monoclonal antibody;
gamma1 heavy chain (1-451) [humanized VH (Homo sapiens IGHV7-4-1*02 (85.70%) -(IGHD)-IGHJ2*01) [8.8.14] (1-121) -Homo sapiens IGHG1*03, G1m3 (CH1 (122-219), hinge (220-234), CH2 (235-344), CH3 (345- 449), CHS (450-451)) (122-451)], (224-214')-disulfide with kappa light chain (1'-214') [humanized V-KAPPA (Homo sapiens IGKV1-9*01 (82.20%) -IGKJ4*01) [6.3.9] (1'-107') - Homo sapiens IGKC*01, Km3 (108'-214')]; dimer (230- 230":233-233")-bisdisulfide
gamma1 heavy chain (1-451) [humanized VH (Homo sapiens IGHV7-4-1*02 (85.70%) -(IGHD)-IGHJ2*01) [8.8.14] (1-121) -Homo sapiens IGHG1*03, G1m3 (CH1 (122-219), hinge (220-234), CH2 (235-344), CH3 (345- 449), CHS (450-451)) (122-451)], (224-214')-disulfide with kappa light chain (1'-214') [humanized V-KAPPA (Homo sapiens IGKV1-9*01 (82.20%) -IGKJ4*01) [6.3.9] (1'-107') - Homo sapiens IGKC*01, Km3 (108'-214')]; dimer (230- 230":233-233")-bisdisulfide
Структура
Иностранные названия
- Sacituzumabum (латинское)
- Sacituzumab (английское)
- Sacituzumab (немецкое)
- Sacituzumab (французское)
- Sacituzumab (испанское)
Подробнее по теме
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