Самротамаб
SamrotamabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2052649-42-8
Химическое название
immunoglobulin G1-kappa, anti-[Homo sapiens LRRC15 (leucine-rich repeat-containing member 15, leucine-rich repeat member induced by beta-amyloid homolog, LIB)], humanized and chimeric monoclonal antibody;
gamma1 heavy chain (1-450) [humanized VH (Homo sapiens IGHV1-2*02 (77.6%) -(IGHD) -IGHJ5*01 (86.7%)) [8.8.13] (1-120) -Homo sapiens IGHG1*01 (CH1 (121-218), hinge (219-233), CH2 (234-343), CH3 (344-448), CHS (449-450)) (121-450)], (223-214')-disulfide with kappa light chain chimeric (1'-214') [Mus musculus V-KAPPA (IGKV10-96*01 (85.30%) -IGKJ1*01 (91.7%)/Homo sapiens IGKV1-39*01 (84.2%) -IGKJ4*01 (100%)) [6.3.9] (1'-107') -Homo sapiens IGKC*01, Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (229-229'':232-232'')-bisdisulfide
gamma1 heavy chain (1-450) [humanized VH (Homo sapiens IGHV1-2*02 (77.6%) -(IGHD) -IGHJ5*01 (86.7%)) [8.8.13] (1-120) -Homo sapiens IGHG1*01 (CH1 (121-218), hinge (219-233), CH2 (234-343), CH3 (344-448), CHS (449-450)) (121-450)], (223-214')-disulfide with kappa light chain chimeric (1'-214') [Mus musculus V-KAPPA (IGKV10-96*01 (85.30%) -IGKJ1*01 (91.7%)/Homo sapiens IGKV1-39*01 (84.2%) -IGKJ4*01 (100%)) [6.3.9] (1'-107') -Homo sapiens IGKC*01, Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (229-229'':232-232'')-bisdisulfide
Структура
Иностранные названия
- Samrotamabum (латинское)
- Samrotamab (английское)
- Samrotamab (немецкое)
- Samrotamab (французское)
- Samrotamab (испанское)
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