Секелазомеран

Rec. INN (наименование, зарегистрированное ВОЗ)

2642373-67-7

messenger RNA (mRNA), 5'-capped, encoding a full-length, codon-optimised pre-fusion stabilised conformation variant (K983P and V984P) of the SARS- CoV-2 (severe acute respiratory syndrome coronavirus 2) spike (S) glycoprotein (Beta variant, B.1.351; based upon GISAID No.
EPI_ISL_2689878), further optimized by two additional stop codons, flanked by an artificial 5' untranslated region (UTR) and a 3' UTR derived from the human alpha globin gene (HBA1) and terminated by a 3' poly(A) tail; contains N¹-methylpseudouridine instead of uridine (all-U>m¹Ψ).

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