Семзуволимаб

Rec. INN (наименование, зарегистрированное ВОЗ)

2409099-32-5

immunoglobulin G1-kappa, anti-[Homo sapiens CD4 (p55, T cell surface antigen T4/Leu-3)], monoclonal antibody;
gamma1 heavy chain (1-448) [VH Musmus/Homsap (Mus musculus IGHV1-75*01 (78.6%) -(IGHD) -IGHJ3*01 (100%)/Homo sapiens IGHV1-2*06 (73.5%) -(IGHD) -IGHJ4*01 (92.3%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG1*01, G1m17,1, G1v48 H84.4 (CH1 K120 (215) (119-216), hinge 1-15 (217-231), CH2 N84.4>H (298) (232-341), CH3 D12 (357), L14 (359) (342-446), CHS (447-448)) (119-448)], (221-218')-disulfide with kappa light chain (1'-218') [V-KAPPA Musmus/Homsap (Mus musculus IGKV3-4*01 (93.9%) -IGKJ2*03 (90.9%) S120>Q (104)/Homo sapiens IGKV4-1*01 (68.3%) -IGKJ2*01 (100%), CDR-IMGT [10.3.9] (27-36.54-56.93-101)) (1'-111') -Homo sapiens IGKC*04 (100%), Km1,2 A45.1 (158), L101 (195) (112'-218')]; dimer (227-227'':230-230'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa

Поделиться этой страницей