Серклутамаб

Rec. INN (наименование, зарегистрированное ВОЗ)

USAN (наименование, принятое к употреблению в США)

immunoglobulin G1-kappa, anti-[Homo sapiens EGFR (epidermal growth factor receptor, receptor tyrosineprotein kinase erbB-1, ERBB1, HER1, HER-1, ERBB)], monoclonal antibody;
gamma1 heavy chain (1-446) [VH (Homo sapiens IGHV4-30-4*01 (81.4%) -(IGHD) -IGHJ4*01 (92.9%)) [9.7.9] (1-116) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 (CH1 R120>K (213) (117- 214), hinge (215-229), CH2 S3>C (238) (230-339), CH3 E12 (355), M 14 (357) (340-444), CHS (445-446)) (117-446)], (219-214')-disulfide with kappa light chain (1'-214') [V-KAPPA (Mus musculus IGKV14-100*01 (86.3%) -IGKJ1*01 (100%)/Homo sapiens IGKV1- 12*01 (74.7%) -IGKJ4*01 (90.9%)) [6.3.9] (1'-107') - Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (225-225'':228-228'')- bisdisulfide

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