Симаравибарт

Rec. INN (наименование, зарегистрированное ВОЗ)

2657609-23-7

immunoglobulin G1-kappa, anti-[Homo sapiens severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein, receptor binding domain (RBD)], Homo sapiens antibody;
gamma1 heavy chain Homo sapiens (1-455) [VH (Homo sapiens IGHV1-69*08 (95.9%) -(IGHD) -IGHJ4*01 (93.3%), CDR-IMGT [8.8.18] (26-33.51-58.97-114)) (1-125) -Homo sapiens IGHG1*03, G1m3, nG1m1, G1v14-49 CH2 A1.3, A1.2, G114, G1v24 CH3 L107, S114 (CH1 R120 (222) (126-223), hinge 1-15 (224-238), CH2 L1.3>A (242), L1.2>A (243), P114>G (337) (239-348), CH3 E12 (364), M14 (366), M107>L (436), N114>S (349-453), CHS (454-455)) (126-455)], (228-210')-disulfide with kappa light chain Homo sapiens (1'-210') [V-KAPPA (Homo sapiens IGKV3-11*01 (97.8%) -IGKJ4*01 (100%), CDR-IMGT [6.3.5] (27-32.50-52.89-93)) (1'-103') -Homo sapiens IGKC*01 (100%), Km3, A45.1 (149), V101 (187) (104'-210')]; dimer (234-234'':237-237'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa

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