Сирелретиген субпарвовек

Sirelretigene suboparvovec

МНН

Rec. INN (наименование, зарегистрированное ВОЗ)

Химическое название

A non-replicating self-complementary adeno-associated virus serotype 8 (scAAV8) vector, encoding human cellular retinaldehydebinding protein 1 (CRALBP).
A recombinant non-replicating self-complementary adenoassociated virus serotype 8 (scAAV8) vector, encoding human cellular retinaldehyde-binding protein 1 (CRALBP) under the control of the retinaldehyde-binding protein 1 promoter (pRLBP1) and terminated with SV40 poly adenylation (polyA) sequence. The vector genome is a head-to-head, self-complementary dimer, with the vector genome cassette located 5' of the mutated internal inverted terminal repeat (Δ-ITR) in a reverse complementary orientation and 3' of the Δ-ITR in a forward orientation.

Структура

Структура Сирелретиген субпарвовек Структура 2 Сирелретиген субпарвовек Структура 3 Сирелретиген субпарвовек

Иностранные названия

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