Соказолимаб
SocazolimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2305043-30-3
Химическое название
immunoglobulin G1-lambda2, anti-[Homo sapiens CD274 (programmed cell death 1 ligand 1, B7H1, B7-H1, PDL1, PD-L1, PDCD1L1, B7 homolog 1)], monoclonal antibody;
gamma1 heavy chain (1-449) [VH (Homo sapiens IGHV1-69*01 (98.0%) -(IGHD) -IGHJ6*01 (94.7%), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*01 (100%), G1m17,1 (CH1 K120 (216) (120-217), hinge 1-15 (218-232), CH2 (233-342), CH3 D12 (358), L14 (360) (343-447), CHS (448-449)) (120-449)], (222-214')-disulfide with lambda2 light chain (1'-215') [V-LAMBDA (Homo sapiens IGLV2-23*02 (90.8%) -IGLJ2*01 (100%), CDR-IMGT [9.3.10] (26-34.52-54.90-99)) (1'-109') -Homo sapiens IGLC2*01 (100%) (110'-215')]; dimer (228-228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO)-K1SV cell line lacking the glutamine synthetase gene (GSKO), glycoform alfa
gamma1 heavy chain (1-449) [VH (Homo sapiens IGHV1-69*01 (98.0%) -(IGHD) -IGHJ6*01 (94.7%), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*01 (100%), G1m17,1 (CH1 K120 (216) (120-217), hinge 1-15 (218-232), CH2 (233-342), CH3 D12 (358), L14 (360) (343-447), CHS (448-449)) (120-449)], (222-214')-disulfide with lambda2 light chain (1'-215') [V-LAMBDA (Homo sapiens IGLV2-23*02 (90.8%) -IGLJ2*01 (100%), CDR-IMGT [9.3.10] (26-34.52-54.90-99)) (1'-109') -Homo sapiens IGLC2*01 (100%) (110'-215')]; dimer (228-228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO)-K1SV cell line lacking the glutamine synthetase gene (GSKO), glycoform alfa
Структура
Иностранные названия
- Socazolimabum (латинское)
- Socazolimab (английское)
- Socazolimab (немецкое)
- Socazolimab (французское)
- Socazolimab (испанское)
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