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Prop. INN (наименование, предложенное ВОЗ)

2927399-38-8

immunoglobulin G1-kappa, anti-[Homo sapiens VSIR (V-set immunoregulatory receptor, B7H5, B7-H5, PDCD1 homolog, PD-1H, stress induced secreted protein 1, SISP1, V-domain Ig suppressor of T cell activation, VISTA)], Homo sapiens monoclonal antibody;
H-gamma1 heavy chain Homo sapiens (1-452) [VH (Homo sapiens IGHV3-48*01 (94.9%) -(IGHD) -IGHJ1*01 (100%), CDR-IMGT [8.8.15] (26-33.51-58.97-111)) (1-122) -Homo sapiens IGHG1*03v (100%) G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14 (CH1 R120>K (219) (123-220), hinge 1-15 (221-235), CH2 (236-345), CH3 E12 (361), M14 (363) (346-450), CHS (451-452)) (123-452)], (225-215')-disulfide with L-kappa light chain Homo sapiens (1'-215') [V-KAPPA (Homo sapiens IGKV1-33*01 (94.7%) -IGKJ4*01 (100%), CDR-IMGT [6.3.10] (27'-32'.50'-52'.89'-98')) (1'-108') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (154'), V101 (192')) (109'-215')]; dimer (231-231'':234-234'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa

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