Солрикитуг

Rec. INN (наименование, зарегистрированное ВОЗ)

2768721-24-8

immunoglobulin G1-kappa, anti-[Homo sapiens CRLF2 (cytokine receptor like factor 2, TSLP, thymic stromal lymphopoietin)], humanized monoclonal antibody;
gamma1 heavy chain humanized (1-450) [VH (Homo sapiens IGHV1-46*01 (83.7%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG1*01 (100%), G1m17,1 CH1 K120, D12, L14 (CH1 K120 (217) (121-218), hinge 1-15 (219-233), CH2 (234-343), CH3 D12 (359), L14 (361) (344-448), CHS (449-450)) (121-450)], (223-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV3-20*01 (85.4%) -IGKJ2*01 (91.7%) L124>V (104), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%), Km3, A45.1 (153'), V101 (191') (108'-214')]; dimer (229-229'':232-232'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DXB11, glycoform alfa

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