Совипостобарт бета

Prop. INN (наименование, предложенное ВОЗ)

2649371-20-8

immunoglobulin G1-kappa, anti-[Homo sapiens CTLA4 (cytotoxic T-lymphocyte associated protein 4, CTLA-4, CD152)], Homo sapiens monoclonal antibody with a cleavable prodomain of 44 amino acids fused at the N-terminal end of the L-kappa light chains;
H-gamma1 heavy chain Homo sapiens (1-447) [VH (Homo sapiens IGHV3-30*01 (94.9%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG1*01v, G1m17,1>G1m3,1 CH1 R120, CH3 D12, L14 (CH1 R120 (215) (119-216), hinge 1-15 (217-231), CH2 (232-341), CH3 D12 (357), L14 (359) (342-446), CHS K2>del (447)) (119-447)], (221-259')-disulfide with L-kappa light chain Homo sapiens fused at its N-terminal end to a cleavable prodomain (1'-259') [prodomain (1'-44') -Homo sapiens V-KAPPA (Homo sapiens IGKV3-20*01 (97.9%) -IGKJ1*01 (100%), CDR-IMGT [7.3.9] (71'-77'.95'-97'.134'-142')) (45'-152') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (198'), V101 (236')) (153'-259')]; dimer (227-227'':230-230'')-bisdisulfide, produced in a Chinese hamster ovary (CHO) cell line lacking the enzyme alpha-(1,6)-fucosyltransferase (FUT8), glycoform beta

Поделиться этой страницей