Стапокибарт

Rec. INN (наименование, зарегистрированное ВОЗ)

2734715-10-5

immunoglobulin G4-kappa, anti-[Homo sapiens IL4R (interleukin 4 receptor, IL4RA, IL-4RA, interleukin 13 receptor, CD124)], humanized monoclonal antibody;
gamma4 heavy chain humanized (1-446) [VH (Homo sapiens IGHV3-23*03 (92.9%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1 (120-217) , hinge 1-12 S10>P (227) (218-229), CH2 L92 (308) (230-339), CH3 (340-444), CHS (445-446)) (120-446)], (133-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV1-33*01 (87.4%) -IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (225-225'':228-228'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, CHOZN® GS-/- ZFN-modified CHO cell line, glycoform alfa

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