Сувемцитуг

Rec. INN (наименование, зарегистрированное ВОЗ)

1610010-57-5

immunoglobulin G1-kappa, anti-[Homo sapiens VEGFA (vascular endothelial growth factor A, VEGF-A, VEGF)], humanized monoclonal antibody;
gamma1 heavy chain humanized (1-452) [VH (Homo sapiens IGHV3-21*01 (74.7%) -(IGHD) -IGHJ2*01 (92.9%), CDR-IMGT [9.8.14] (26-34.52-59.98-111)) (1-122) -Homo sapiens IGHG1*01 (100%), G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120 (219) (123-220), hinge 1-15 (221-235), CH2 (236-345), CH3 D12 (361), L14 (363) (346-450), CHS (451-452)) (123-452)], (225-219')-disulfide with kappa light chain humanized (1'-219') [V-KAPPA (Homo sapiens IGKV1-6*01 (85.4%) -IGKJ4*01 (100%), CDR-IMGT [8.3.12] (27-34.52-54.91-102)) (1'-112') -Homo sapiens IGKC*01 (100%), Km3, A45.1 (158), V101 (196) (113'-219')]; dimer (231-231'':234-234'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DG44, glycoform alfa

Поделиться этой страницей