Табитуксимаб

Rec. INN (наименование, зарегистрированное ВОЗ)

1644134-10-0

immunoglobulin G1-kappa, anti-[Homo sapiens FZD10 (frizzled class receptor 10, frizzled family receptor 10, Frizzled-10, CD350)], chimeric monoclonal antibody;
gamma1 heavy chain chimeric (1-448) [Mus musculus VH (IGHV14-3*02 (99.0%) -(IGHD) -IGHJ3*01 (100%)) [8.8.11] (1-118) -Homo sapiens IGHG1*01, G1m17,1 (CH1 K120 (215) (119-216), hinge (217-231), CH2 (232- 341), CH3 D12 (357), L14 (359) (342-446), CHS (447-448)) (119-448)], (221-214')-disulfide with kappa light chain chimeric (1'-214') [Mus musculus V-KAPPA (IGKV12- 46*01 (98.9%) -IGKJ2*01 (100%)) [6.3.9] (1'-107') -Homo sapiens IGKC*01, Km3 A45.1 (153), V101 (191) (108'- 214')]; dimer (227-227'':230-230'')-bisdisulfide

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