Таниралейцел

Rec. INN (наименование, зарегистрированное ВОЗ)

Allogeneic natural killer (NK) cells derived from CD34+ human placental stem/progenitor cells. The cells are expanded and differentiated in the presence of cytokines including thrombopoietin, SCF, Flt3 ligand, IL-7, IL-15 and IL-2 to generate the NK cell population. Cells (on average >95% of the cells) are CD56+/CD3- and have detectable levels of CD94, NKG2D and CD16. The cells secrete IFN-γ, perforin and granzyme B, and have cytolytic activity against human tumour cell lines.

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