Тарперпрамиг
TarperprumigМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2630946-41-5
Химическое название
immunoglobulin single chain VH-VH', anti-[Homo sapiens CFP (complement factor properdin, properdin)] and anti-[Homo sapiens ALB (albumin, human serum albumin, HAS)], humanized monoclonal antibody, bispecific, bivalent;
single chain (sc) VH-VH' (1-256) [humanized VH anti-CFP (Vicugna pacos IGHV3-3*01 (81.6%) -(IGHD) -IGHJ3*01 (92.3%)/Homo sapiens IGHV3-11*05 (80.4%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.7.17] (26-33.51-57.96-112) (1-123)) -15-mer tris(tetraglycyl-glutamyl) linker (124-138) -humanized VH anti-ALB (Vicugna pacos 3S3*01 (82.3%) -(IGHD) -IGHJ4*01, Q123>L (92.3%)/Homo sapiens IGHV3-23*01 (80.0%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.7.13] (163-170.188-194.233-245) (139-256))], produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV, non-glycosylated
single chain (sc) VH-VH' (1-256) [humanized VH anti-CFP (Vicugna pacos IGHV3-3*01 (81.6%) -(IGHD) -IGHJ3*01 (92.3%)/Homo sapiens IGHV3-11*05 (80.4%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.7.17] (26-33.51-57.96-112) (1-123)) -15-mer tris(tetraglycyl-glutamyl) linker (124-138) -humanized VH anti-ALB (Vicugna pacos 3S3*01 (82.3%) -(IGHD) -IGHJ4*01, Q123>L (92.3%)/Homo sapiens IGHV3-23*01 (80.0%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.7.13] (163-170.188-194.233-245) (139-256))], produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV, non-glycosylated
Структура
Иностранные названия
- Tarperprumigum (латинское)
- Tarperprumig (английское)
- Tarperprumig (немецкое)
- Tarperprumig (французское)
- Tarperprumig (испанское)
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