Теликибарт

Prop. INN (наименование, предложенное ВОЗ)

2618667-96-0

immunoglobulin G1-kappa, anti-[Homo sapiens IL4R (interleukin 4 receptor, IL4RA, IL-4RA, interleukin 13 receptor, CD124)], Homo sapiens monoclonal antibody;
H-gamma1 heavy chain Homo sapiens (1-455) [VH (Homo sapiens IGHV3-23*04 (92.9%) -(IGHD) -IGHJ6*01 (82.4%), CDR-IMGT [8.8.18] (26-33.51-58.97-114)) (1-125) -Homo sapiens IGHG1*03, G1m3, nG1m1 CH1 R120, CH3 E12, M14, G1v39 CH2 F1.3, E1.2, S116 (CH1 R120 (222) (126-223), hinge 1-15 (224-238), CH2 L1.3>F (242), L1.2>E (243), P116>S (339) (239-348), CH3 E12 (364), M14 (366) (349-453), CHS (454-455)) (126-455)], (228-219')-disulfide with L-kappa light chain Homo sapiens (1'-219') [V-KAPPA (Homo sapiens IGKV2-28*01 (92.0%) -IGKJ2*01 (100%), CDR-IMGT [11.3.9] (27'-37'.55'-57'.94'-102')) (1'-112') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (158'), V101 (196')) (113'-219')]; dimer (234-234'':237-237'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa

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