Темелимаб

Rec. INN (наименование, зарегистрированное ВОЗ)

DB15634

1393641-34-3

immunoglobulin G4-kappa, anti-[Homo sapiens endogenous retrovirus (HERV) family W multiple sclerosis-associated retrovirus (MRSV) envelope protein], humanized monoclonal antibody;
gamma4 heavy chain (1-443) [humanized VH (Homo sapiens IGHV1- 46*01 (81.2%) -(IGHD)-IGHJ4*01 (92.9%)) [8.8.9] (1-116) -Homo sapiens IGHG4*01 (CH1 (117-214), hinge S10>P (224) (215-226), CH2 (227- 336), CH3 (337-441), CHS (442-443)) (117-443)], (130-213')-disulfide with kappa light chain (1'-213') [humanized V-KAPPA (Homo sapiens IGKV1-39*01 (81.9%) -IGKJ4*01 (100%)) [5.3.9] (1'-106') -Homo sapiens IGKC*01, Km3 A45.1 (152), V101 (190) (107'-213')]; dimer (222- 222":225-225")-bisdisulfide

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