Темтокибарт

Rec. INN (наименование, зарегистрированное ВОЗ)

2639874-57-8

immunoglobulin G1-lambda2, anti-[Homo sapiens IL22RA1 interleukin 22 receptor subunit alpha 1, IL22R)], humanized monoclonal antibody;
gamma1 heavy chain humanized (1-450) [VH (Homo sapiens IGHV3-NL1*01 (89.8%) -(IGHD) -IGHJ5*01 (92.3%), CDR-IMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, CH3 D12, L14, IGHG1v36 CH2 Q84.4 (CH1 K120 (217) (121-218), hinge 1-15 (219-233), CH2 N84.4>Q (300) (234-343), CH3 D12 (359), L14 (361) (344-448), CHS (449-450)) (121-450)], (223-208')-disulfide with lambda light chain humanized (1'-209') [V-LAMBDA (Homo sapiens IGLV3-9*02 (80.9%) -IGLJ2*01 (100%), CDR-IMGT [2.3.10] (26-27.45-47.84-93)) (1'-103') -Homo sapiens IGLC2*01 (100%) (104'-209')]; dimer (229-229'':232-232'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV lacking the glutamine synthetase (GS-KO) gene, non-glycosylated

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