Тимцевибарт

Rec. INN (наименование, зарегистрированное ВОЗ)

2857862-27-0

immunoglobulin G1-kappa, anti-[severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein, receptor binding domain (RBD)], Homo sapiens monoclonal antibody;
gamma1 heavy chain Homo sapiens (1-445) [VH (Homo sapiens IGHV3-66*01 (96.9%) -(IGHD) -IGHJ3*02 (100%), CDR-IMGT [8.7.10] (26-33.51-57.96-105)) (1-116) -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, CH3 D12, L14, G1v50-79 CH2 delE1.4, P1.3, V1.2, A1.A, G27, Q110, S115 (CH1 K120 (213) (117-214), hinge 1-15 (215-229), CH2 E1.4>del, L1.3>P (232), L1.2>V (233), G1.1>A (234), D27>G (263), A110>Q (325), A115>S (328) (230-338), CH3 D12 (354), L14 (356) (339-443), CHS (444-445)) (117-445)], (219-215')-disulfide with kappa light chain Homo sapiens (1'-215') [V-KAPPA (Homo sapiens IGKV1-9*01 (97.9%) -IGKJ3*01 (100%), CDR-IMGT [6.3.10] (27'-32'.50'-52'.89'-98')) (1'-108') -Homo sapiens IGKC*01 (100%), Km3, A45.1 (154'), V101 (192') (109'-215')]; dimer (225-225'':228-228'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, derived from the cell line CHO-K1, glycoform alfa

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