Тирноветмаб
TirnovetmabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
USAN (наименование, принятое к употреблению в США)
CAS
2364504-80-1
Химическое название
immunoglobulin G2-kappa, anti-[Canis lupus familiaris IL31 (interleukin 31)], caninized monoclonal antibody;
gamma2 heavy chain caninized 1-453) [VH caninized (Canis lupus familiaris IGHV4-1*01 (61.2%) -(IGHD) -IGHJ4*01 (100%)) CDR-IMGT [8.7.12] (26-33.51-57.96-107) (1-118) -Canis lupus familiaris IGHG2*02 (100%) (CH1 (119-215), hinge 1-19 (216-234), CH2 (235-344), CH3 (345-451), CHS (452-453)) (119-453)], (133-217')-disulfide with kappa light chain caninized (1'-221') [V-KAPPA caninized (Canis lupus familiaris IGKV3-18*01 (63.8%) -IGKJ3*01 (83.3%) Q120>G (104)) CDR-IMGT [10.3.9] (27-36.54-56.93-101) (1'-111') -Canis lupus familiaris IGKC*01 (100%) (112'-221')]; dimer (230-230'':233-233'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-K1 cell line, glycoform alfa
gamma2 heavy chain caninized 1-453) [VH caninized (Canis lupus familiaris IGHV4-1*01 (61.2%) -(IGHD) -IGHJ4*01 (100%)) CDR-IMGT [8.7.12] (26-33.51-57.96-107) (1-118) -Canis lupus familiaris IGHG2*02 (100%) (CH1 (119-215), hinge 1-19 (216-234), CH2 (235-344), CH3 (345-451), CHS (452-453)) (119-453)], (133-217')-disulfide with kappa light chain caninized (1'-221') [V-KAPPA caninized (Canis lupus familiaris IGKV3-18*01 (63.8%) -IGKJ3*01 (83.3%) Q120>G (104)) CDR-IMGT [10.3.9] (27-36.54-56.93-101) (1'-111') -Canis lupus familiaris IGKC*01 (100%) (112'-221')]; dimer (230-230'':233-233'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-K1 cell line, glycoform alfa
Структура
Иностранные названия
- Tirnovetmabum (латинское)
- Tirnovetmab (английское)
- Tirnovetmab (немецкое)
- Tirnovetmab (французское)
- Tirnovetmab (испанское)
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