Тобевибарт
TobevibartМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2645440-65-7
Химическое название
immunoglobulin G1-lambda, anti-[HBV (hepatitis B virus) surface envelope protein], Homo sapiens monoclonal antibody;
gamma1 heavy chain Homo sapiens (1-449) [VH (Homo sapiens IGHV3-7*01 (85.6%) -(IGHD) -IGHJ6*01 (93.3%)) [8.8.12] (26-33.51-58.97-108) (1-119) -Homo sapiens IGHG1*01, G1m17,1, G1v45 CH2 A1.1, L115, E117, G1v24 CH3 L107, S114 (CH1 K120 (216) (120-217), hinge 1-15 (218-232), CH2 G1.1>A (238) , A115>L (332), I117>E (334) (233-342), CH3 D12 (358), L14 (360), M107>L (430), N114>S (436) (343-447), CHS (448-449)) (120-449)], (222-211')-disulfide with lambda light chain Homo sapiens (1'-212') [V-LAMBDA (Homo sapiens IGLV3-1*01 (81.9%) -IGLJ2*01 (91,7%)) [6.3.9] (26-31.49-51.88-96) (1'-106') -Homo sapiens IGLC2*01 (100%) (107'-212')]; dimer (228-228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa
gamma1 heavy chain Homo sapiens (1-449) [VH (Homo sapiens IGHV3-7*01 (85.6%) -(IGHD) -IGHJ6*01 (93.3%)) [8.8.12] (26-33.51-58.97-108) (1-119) -Homo sapiens IGHG1*01, G1m17,1, G1v45 CH2 A1.1, L115, E117, G1v24 CH3 L107, S114 (CH1 K120 (216) (120-217), hinge 1-15 (218-232), CH2 G1.1>A (238) , A115>L (332), I117>E (334) (233-342), CH3 D12 (358), L14 (360), M107>L (430), N114>S (436) (343-447), CHS (448-449)) (120-449)], (222-211')-disulfide with lambda light chain Homo sapiens (1'-212') [V-LAMBDA (Homo sapiens IGLV3-1*01 (81.9%) -IGLJ2*01 (91,7%)) [6.3.9] (26-31.49-51.88-96) (1'-106') -Homo sapiens IGLC2*01 (100%) (107'-212')]; dimer (228-228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa
Структура
Иностранные названия
- Tobevibartum (латинское)
- Tobevibart (английское)
- Tobevibart (немецкое)
- Tobévibart (французское)
- Tobevibart (испанское)
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