Тоногенконцел

Rec. INN (наименование, зарегистрированное ВОЗ)

Allogeneic primary human chondrocytes transduced with a retroviral vector expressing human transforming growth factor-beta1 (TGF-β1). A master cell bank of primary human chondrocytes, grown from cartilage tissue obtained from the surgical excision of a polydactyly finger from a three-year-old female donor, was prepared. After transduction of cells from the master cell bank, a single clonal population was selected using limiting dilution and submitted to irradiation.
Cells express TGF-β1, Type I and Type II collagen as well as Type I and Type II TGF-β1 receptors; they lack expression of gag and pol genes.

Поделиться этой страницей