Торудокимаб
TorudokimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
Drugbank
DB16671
CAS
2241728-76-5
Химическое название
immunoglobulin G4-kappa, anti-[Homo sapiens IL33 (interleukin 33, interleukin-1 family member 11, IL1F11, nuclear factor for high endothelial venules, NF-HEV)], monoclonal antibody;
gamma4 heavy chain (1-449) [VH (Homo sapiens IGHV3-23*04 (95.9%) -(IGHD) -IGHJ3*02 (87.5%) M123>L (118)) CDR-IMGT [8.8.16] (26-33.51-58.97-112) (1-123) -Homo sapiens IGHG4*01 G4v5 h P10, G4v4 CH2 A1.3, A1.2 (CH1 (124-221), hinge 1-12 S10>P (231) (222-233), CH2 F1.3>A (237), L1.2>A (238) (234-343), CH3 (344-448), CHS K>del (449)) (124-449)], (137-215')-disulfide with kappa light chain (1'-215') [V-KAPPA (Homo sapiens IGKV3-20*01 (88.5%) -IGKJ4*01 (91.7%)) CDR-IMGT [6.3.10] (27-32.50-52.89-98) (1'-108') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (154), V101 (192) (109'-215')]; dimer (229-229'':232-232'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-K1 cell line, glycoform alfa
gamma4 heavy chain (1-449) [VH (Homo sapiens IGHV3-23*04 (95.9%) -(IGHD) -IGHJ3*02 (87.5%) M123>L (118)) CDR-IMGT [8.8.16] (26-33.51-58.97-112) (1-123) -Homo sapiens IGHG4*01 G4v5 h P10, G4v4 CH2 A1.3, A1.2 (CH1 (124-221), hinge 1-12 S10>P (231) (222-233), CH2 F1.3>A (237), L1.2>A (238) (234-343), CH3 (344-448), CHS K>del (449)) (124-449)], (137-215')-disulfide with kappa light chain (1'-215') [V-KAPPA (Homo sapiens IGKV3-20*01 (88.5%) -IGKJ4*01 (91.7%)) CDR-IMGT [6.3.10] (27-32.50-52.89-98) (1'-108') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (154), V101 (192) (109'-215')]; dimer (229-229'':232-232'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-K1 cell line, glycoform alfa
Структура
Иностранные названия
- Torudokimabum (латинское)
- Torudokimab (английское)
- Torudokimab (немецкое)
- Torudokimab (французское)
- Torudokimab (испанское)
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