Туренкибарт
TurenkibartМНН
Prop. INN (наименование, предложенное ВОЗ)
CAS
2761187-73-7
Химическое название
immunoglobulin G1-kappa, anti-[Homo sapiens IL17A (Interleukin 17A, IL-17), humanized monoclonal antibody;
H-gamma1 heavy chain humanized (1-448) [VH (Homo sapiens IGHV1-69-2*01 (86.5%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, CH3 D12, L14, G1v78 CH3 L107, A114 (CH1 K120 (215) (119-216), hinge 1-15 (217-231), CH2 (232-341), CH3 D12 (357), L14 (359), M107>L (429), N114>A (435) (342-446), CHS (447-448)) (119-448)], (221-220')-disulfide with L-kappa light chain humanized (1'-220') [V-KAPPA (Homo sapiens IGKV4-1*01 (90.1%) -IGKJ3*01 (100%), CDR-IMGT [12.3.9] (27'-38'.56'-58'.95'-103')) (1'-113') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (159'), V101 (197')) (114'-220')]; dimer (227-227'':230-230'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
H-gamma1 heavy chain humanized (1-448) [VH (Homo sapiens IGHV1-69-2*01 (86.5%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, CH3 D12, L14, G1v78 CH3 L107, A114 (CH1 K120 (215) (119-216), hinge 1-15 (217-231), CH2 (232-341), CH3 D12 (357), L14 (359), M107>L (429), N114>A (435) (342-446), CHS (447-448)) (119-448)], (221-220')-disulfide with L-kappa light chain humanized (1'-220') [V-KAPPA (Homo sapiens IGKV4-1*01 (90.1%) -IGKJ3*01 (100%), CDR-IMGT [12.3.9] (27'-38'.56'-58'.95'-103')) (1'-113') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (159'), V101 (197')) (114'-220')]; dimer (227-227'':230-230'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
Структура
Иностранные названия
- Turenkibartum (латинское)
- Turenkibart (английское)
- Turenkibart (немецкое)
- Turenkibart (французское)
- Turenkibart (испанское)
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