Уфренмеран

Rec. INN (наименование, зарегистрированное ВОЗ)

2749556-96-3

messenger RNA (mRNA), 5'-capped, encoding the codon- optimized receptor binding domain (RBD) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, Wuhan-Hu-1 isolate, GenBank: MN908947.3) spike (S) glycoprotein, expressed as a fusion protein with the S glycoprotein signal peptide, flanked by 5' and 3' untranslated regions (UTRs) derived from the human β-globin gene (GenBank ID: NM_000518.5) and a 3' polyadenylation (polyA) tail; contains 5-methyluridine instead of uridine (all-U>5-Me-U) and 5-methylcytidine instead of cytidine (all-C>5-Me-C).

Поделиться этой страницей