Уленистамаб
UlenistamabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2415259-90-2
Химическое название
immunoglobulin G1-kappa, anti-[Homo sapiens PAUF (pancreatic adenocarcinoma up-regulated factor)], humanized monoclonal antibody;
gamma1 heavy chain humanized (1-451) [VH (Homo sapiens IGHV1-2*02 (90.8%) -(IGHD) -IGHJ6*01 (90.9%) T123>L (116), CDR-IMGT [8.8.14] (26-33.51-58.97-110)) (1-121) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 (CH1 R120>K (218) (122-219), hinge 1-15 (220-234), CH2 (235-344), CH3 E12 (360), M14 (362) (345-449), CHS (450-451)) (122-451)], (224-219')-disulfide with kappa light chain humanized (1'-219') [V-KAPPA (Homo sapiens IGKV4-1*01 (91.9%) -IGKJ2*01 (91.7%) L124>V (109), CDR-IMGT [12.3.8] (27-38.56-58.95-102)) (1'-112') -Homo sapiens IGKC*01, Km3 T1.3>S (114), A45.1 (158), V101 (196) (113'-219')]; dimer (230-230'':233-233'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-K1 cell line, glycoform alfa
gamma1 heavy chain humanized (1-451) [VH (Homo sapiens IGHV1-2*02 (90.8%) -(IGHD) -IGHJ6*01 (90.9%) T123>L (116), CDR-IMGT [8.8.14] (26-33.51-58.97-110)) (1-121) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 (CH1 R120>K (218) (122-219), hinge 1-15 (220-234), CH2 (235-344), CH3 E12 (360), M14 (362) (345-449), CHS (450-451)) (122-451)], (224-219')-disulfide with kappa light chain humanized (1'-219') [V-KAPPA (Homo sapiens IGKV4-1*01 (91.9%) -IGKJ2*01 (91.7%) L124>V (109), CDR-IMGT [12.3.8] (27-38.56-58.95-102)) (1'-112') -Homo sapiens IGKC*01, Km3 T1.3>S (114), A45.1 (158), V101 (196) (113'-219')]; dimer (230-230'':233-233'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-K1 cell line, glycoform alfa
Структура
Иностранные названия
- Ulenistamabum (латинское)
- Ulenistamab (английское)
- Ulenistamab (немецкое)
- Ulénistamab (французское)
- Ulenistamab (испанское)
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