Улиледлимаб
UliledlimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
Drugbank
DB16675
CAS
2378407-27-1
Химическое название
immunoglobulin G1-kappa, anti-[Homo sapiens NT5E (5'-nucleotidase ecto, 5' nucleotidase, NT5, eN, eNT NTE, CALJA, CD73)], monoclonal antibody;
gamma1 heavy chain (1-450) [VH (Homo sapiens IGHV4-38-2*01 (87.6%) -(IGHD) -IGHJ6*01 (100%)) CDR-IMGT [9.7.13] (26-34.52-58.97-109) (1-120) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 (CH1 R>K 120 (217) (121-218), hinge 1-15 (219-233), CH2 N84.4>A (300) (234-343), CH3 E12 (359), M14 (361) (344-448), CHS(449-450)) (121-450)], (223-213')-disulfide with kappa light chain (1'-215') [V-KAPPA (Mus musculus IGKV4-72*01 (81.1%) -IGKJ1*01 (90.9%) L124>V (103)/Homo sapiens IGKV3-11*01 (77.9%) -IGKJ4*01 (100%)) CDR-IMGT [5.3.9] (26-31.59-51.88-96) (1'-106') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (152), V101 (190) (107'-213')]; dimer (229-229'':232-232'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-K1 cell line, non-glycosylated
gamma1 heavy chain (1-450) [VH (Homo sapiens IGHV4-38-2*01 (87.6%) -(IGHD) -IGHJ6*01 (100%)) CDR-IMGT [9.7.13] (26-34.52-58.97-109) (1-120) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 (CH1 R>K 120 (217) (121-218), hinge 1-15 (219-233), CH2 N84.4>A (300) (234-343), CH3 E12 (359), M14 (361) (344-448), CHS(449-450)) (121-450)], (223-213')-disulfide with kappa light chain (1'-215') [V-KAPPA (Mus musculus IGKV4-72*01 (81.1%) -IGKJ1*01 (90.9%) L124>V (103)/Homo sapiens IGKV3-11*01 (77.9%) -IGKJ4*01 (100%)) CDR-IMGT [5.3.9] (26-31.59-51.88-96) (1'-106') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (152), V101 (190) (107'-213')]; dimer (229-229'':232-232'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-K1 cell line, non-glycosylated
Структура
Иностранные названия
- Uliledlimabum (латинское)
- Uliledlimab (английское)
- Uliledlimab (немецкое)
- Ulilédlimab (французское)
- Uliledlimab (испанское)
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