Умикибарт

Rec. INN (наименование, зарегистрированное ВОЗ)

2851478-58-3

immunoglobulin G4-kappa, anti-[Homo sapiens HGF (hepatocyte growth factor, scatter factor, SF, hepatopoeitin A)], humanized monoclonal antibody;
H-gamma4 heavy chain humanized (1-443) [VH (Homo sapiens IGHV3-23*04 (89.8%) -(IGHD) -IGHJ1*01 (100%), CDR-IMGT [8.8.9] (26-33.51-58.97-105)) (1-116) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10, G4v3 CH2 E1.2 (CH1 (117-214), hinge 1-12 S10>P (224) (215-226), CH2 L92 (305), L1.2>E (231) (227-336), CH3 (337-441), CHS (442-443)) (117-443)], (130-215')-disulfide with L-kappa light chain humanized (1'-215') [V-KAPPA (Homo sapiens IGKV1-13*02 (94.3%) -IGKJ1*01 (100%), CDR-IMGT [6.3.10] (27'-32'.50'-52'.89'-98')) (1'-108') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (154'), V101 (192') (109'-115')]; dimer (222-222'':225-225'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DG44, glycoform alfa

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