Унаснемаб
UnasnemabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2379805-59-9
Химическое название
immunoglobulin G1-kappa, anti-[Homo sapiens RGMA (repulsive guidance molecule BMP co-receptor a, RGM)], monoclonal antibody;
gamma1 heavy chain (1-446) [VH (Mus musculus IGHV6-6*01 (87%) -(IGHD) -IGHJ1*01 (90.9%)/Homo sapiens IGHV3-49*04 (85%) -(IGHD) -IGHJ6*04 (100%)) CDR-IMGT [8.10.7] (26-33.51-60.99-105) (1-116) -Homo sapiens IGHG1*01 (100%), G1m17,1 (CH1 K120 (213) (117-214), hinge 1-15 (215-229), CH2 (230-339), CH3 D12 (355), L14 (357) (340-444), CHS (445-446)) (117-446)], (219-214')-disulfide with kappa light chain (1'-214') [V-KAPPA (Homo sapiens IGKV1-12*01 (87.4%) -IGKJ4*01 (81.8%)) CDR-IMGT [6.3.9] (27-32.50-52.89-97) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (225-225'':228-228'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
gamma1 heavy chain (1-446) [VH (Mus musculus IGHV6-6*01 (87%) -(IGHD) -IGHJ1*01 (90.9%)/Homo sapiens IGHV3-49*04 (85%) -(IGHD) -IGHJ6*04 (100%)) CDR-IMGT [8.10.7] (26-33.51-60.99-105) (1-116) -Homo sapiens IGHG1*01 (100%), G1m17,1 (CH1 K120 (213) (117-214), hinge 1-15 (215-229), CH2 (230-339), CH3 D12 (355), L14 (357) (340-444), CHS (445-446)) (117-446)], (219-214')-disulfide with kappa light chain (1'-214') [V-KAPPA (Homo sapiens IGKV1-12*01 (87.4%) -IGKJ4*01 (81.8%)) CDR-IMGT [6.3.9] (27-32.50-52.89-97) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (225-225'':228-228'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
Структура
Иностранные названия
- Unasnemabum (латинское)
- Unasnemab (английское)
- Unasnemab (немецкое)
- Unasnémab (французское)
- Unasnemab (испанское)
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