Вамикибарт

Rec. INN (наименование, зарегистрированное ВОЗ)

2744320-12-3

immunoglobulin G2-kappa, anti-[Homo sapiens IL6 (interleukin 6)], humanized and chimeric monoclonal antibody;
gamma2 heavy chain humanized (1-448) [VH (Homo sapiens IGHV1-69*11 (86.7%) -(IGHD) -IGHJ5*02 (90.9%) L123>T (117), CDR-IMGT [8.8.15] (26-33.51- 58.97-111)) (1-122) -Homo sapiens IGHG2*01, G2m.. CH2 V45.1, G2v8 CH2 A93 (CH1 (123-220), hinge 1- 12 (221-232), CH2 V45.1 (283), H93>A (311) (233- 341), CH3 (342-446), CHS (447-448)) (123-448)], (136-218')-disulfide with kappa light chain chimeric (1'- 218') [V-KAPPA Musmus/Homsap (Mus musculus IGKV3-2*01 (79.8%) -IGKJ2*03 (90.9%) S120>Q (104)/Homo sapiens IGKV4-1*01 (79.2%) -IGKJ2*01 (100%), CDR-IMGT [10.3.9] (27-36.54-56.93-101)) (1'- 111') -Homo sapiens IGKC*01, Km3 A45.1 (157), V101 (195) (112'-218')]; dimer (224-224'':225- 225'':228-228'':231-231'')-tetrakisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO- K1M, glycoform alfa

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