Векантоксатуг
VecantoxatugМНН
Prop. INN (наименование, предложенное ВОЗ)
CAS
2956766-52-0
Химическое название
immunoglobulin G1-kappa, anti-[Clostridium tetani tetanus toxin (TeNT, neurotoxin)], humanized monoclonal antibody;
H-gamma1 heavy chain humanized (1-445) [VH (Homo sapiens IGHV1-69*02 (81.4%) -(IGHD) -IGHJ4*01 (85.7%) L123>M (110), CDR-IMGT [8.8.8] (26-33.51-58.97-104)) (1-115) -Homo sapiens IGHG1*03 (100%) G1m3, nG1m1 CH1 R120, CH3 E12, M14 (CH1 R120 (212) (116-213), hinge 1-15 (214-228), CH2 (229-338), CH3 E12 (354), M14 (356) (339-443), CHS (444-445)) (116-445)], (218-214')-disulfide with L-kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV1-NL1*01 (86.3%) -IGKJ2*01 (100%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')]; dimer (224-224'': 227-227'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
H-gamma1 heavy chain humanized (1-445) [VH (Homo sapiens IGHV1-69*02 (81.4%) -(IGHD) -IGHJ4*01 (85.7%) L123>M (110), CDR-IMGT [8.8.8] (26-33.51-58.97-104)) (1-115) -Homo sapiens IGHG1*03 (100%) G1m3, nG1m1 CH1 R120, CH3 E12, M14 (CH1 R120 (212) (116-213), hinge 1-15 (214-228), CH2 (229-338), CH3 E12 (354), M14 (356) (339-443), CHS (444-445)) (116-445)], (218-214')-disulfide with L-kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV1-NL1*01 (86.3%) -IGKJ2*01 (100%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')]; dimer (224-224'': 227-227'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
Структура
Иностранные названия
- Vecantoxatugum (латинское)
- Vecantoxatug (английское)
- Vecantoxatug (немецкое)
- Vécantoxatug (французское)
- Vecantoxatug (испанское)
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