Велигротуг

Rec. INN (наименование, зарегистрированное ВОЗ)

2728655-31-8

immunoglobulin G1-kappa, anti-[Homo sapiens IGF1R (insulin-like growth factor 1 receptor, IGF1-R, IGF-1R, CD221)], chimeric monoclonal antibody;
gamma1 heavy chain chimeric (1-454) [VH (Mus musculus IGHV1S81*02 (91.8%) -(IGHD) -IGHJ1*01 (93.8%), CDR-IMGT [8.8.17] (26-33.51-58.97-113)) (1-124) -Homo sapiens IGHG1*01 (100%), G1m17,1 CH1 K120, D12, L14 (CH1 K120 (221) (125-222), hinge 1- 5 (223-237), CH2 (238-347), CH3 D12 (363), L14 (365) (348-452), CHS (453-454)) (125-454)], (227-219')-disulfide with kappa light chain chimeric (1'-219') [V-KAPPA (Mus musculus IGKV1-117*01 (93.0%) - IGKJ1*02 (100%), CDR-IMGT [11.3.9] (27-37.55- 57.94-102)) (1'-112') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (158), V101 (196) (113'-219')]; dimer (233- 233'':236-236'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, derived from the cell line CHO-K1, glycoform alfa

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