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Rec. INN (наименование, зарегистрированное ВОЗ)

2649466-18-0

immunoglobulin G1-kappa, anti-[Homo sapiens HAVCR2 (hepatitis A virus cellular receptor 2, T cell immunoglobulin and mucin domains family member 3, TIM3, TIM-3, TIMD3, CD366)], Homo sapiens monoclonal antibody;
gamma1 heavy chain Homo sapiens (1-449) [VH (Homo sapiens IGHV3-23*04 (94.9%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG1*03, G1m3, nG1m1 CH1 R120, CH3 E12, M14, IGHG1v29 CH2 A84.4 (CH1 R120 (217) (121-218), hinge 1-15 (219-233), CH2 N84.4>A (300) (234-343), CH3 E12 (359), M14 (361) (344-448), CHS K2>del (449)) (121-449)], (223-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V- KAPPA (Homo sapiens IGKV3D-11*02 (96.7%) -IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (229-229'':232-232'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV lacking the glutamine synthetase (GS-KO) gene, non-glycosylated

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