Кселигекимаб
XeligekimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2382921-73-3
Химическое название
immunoglobulin G4-kappa, anti-[Homo sapiens IL17A (interleukin 17A, IL-17A)], monoclonal antibody;
gamma4 heavy chain (1-454) [VH (Homo sapiens IGHV3-7*01 (88.8%) -(IGHD) -IGHJ2*01 (100%), CDR-IMGT [8.8.20] (26-33.51-58.97-116)) (1-127) -Homo sapiens IGHG4*01, G4v5 h P10 (CH1 (128-225), hinge 1-12 S10>P (235) (226-237), CH2 (238-347), CH3 (348-452), CHS (453-454)) (128-454)], (141-214')-disulfide with kappa light chain (1'-214') [V-KAPPA (Homo sapiens IGKV1-6*01 (89.1%) -IGKJ1*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (233-233'':236-236'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-S cell line, glycoform alfa
gamma4 heavy chain (1-454) [VH (Homo sapiens IGHV3-7*01 (88.8%) -(IGHD) -IGHJ2*01 (100%), CDR-IMGT [8.8.20] (26-33.51-58.97-116)) (1-127) -Homo sapiens IGHG4*01, G4v5 h P10 (CH1 (128-225), hinge 1-12 S10>P (235) (226-237), CH2 (238-347), CH3 (348-452), CHS (453-454)) (128-454)], (141-214')-disulfide with kappa light chain (1'-214') [V-KAPPA (Homo sapiens IGKV1-6*01 (89.1%) -IGKJ1*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (233-233'':236-236'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-S cell line, glycoform alfa
Структура
Иностранные названия
- Xeligekimabum (латинское)
- Xeligekimab (английское)
- Xeligekimab (немецкое)
- Xéligékimab (французское)
- Xeligekimab (испанское)
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