Залтенибарт

Prop. INN (наименование, предложенное ВОЗ)

2527079-60-1

immunoglobulin G4-kappa, anti-[Homo sapiens MASP3 (mannan-binding lectin-associated serine protease-3)];
H-gamma4 heavy chain (1-440) [VH Musmus/Homsap (Mus musculus IGHV1-9*01 (79.6%) -(IGHD) -IGHJ3*01 (90.9%) A128>S (113)/Homo sapiens IGHV1-46*01 (79.6%) -(IGHD) -IGHJ1*01 (100%), CDR-IMGT [8.8.6] (26-33.51-58.97-102)) (1-113) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10, G4v24 CH3 L107, S114 (CH1 (114-211), hinge 1-12 S10>P (221) (212-223), CH2 L92 (302) (224-333), CH3 M107>L (421), N114>S (427) (334-438), CHS (439-440)) (114-440)], (127-219')-disulfide with L-kappa light chain (1'-219') [V-KAPPA (Homo sapiens IGKV4-1*01 (91.1%)  -IGKJ1*01 (100%), CDR-IMGT [12.3.8] (27'-38'.56'-58'.95'-102')) (1'-112') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (158'), V101 (196') (113'-219')]; dimer (219-219'':222-222'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DG44, glycoform alfa

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