Замеримаб
ZamerovimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2419087-87-7
Химическое название
immunoglobulin G1-kappa, anti-[rabies lyssavirus (rabies virus, RABV) spike glycoprotein G], humanized monoclonal antibody;
gamma1 heavy chain humanized (1-451) [VH (Homo sapiens IGHV1-3*01 (80.6%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.14] (26-33.51-58.97-110)) (1-121) -Homo sapiens IGHG1*01 (100%), G1m17,1 (CH1 K120 (218) (122-219), hinge 1-15 (220-234), CH2 (235-344), CH3 D12 (360), L14 (362) (345-449), CHS (450-451)) (122-451)], (224-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV1-16*01 (86.3%) -IGKJ2*02 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (230-230'':233-233'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-DG44 cell line, glycoform alfa
gamma1 heavy chain humanized (1-451) [VH (Homo sapiens IGHV1-3*01 (80.6%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.14] (26-33.51-58.97-110)) (1-121) -Homo sapiens IGHG1*01 (100%), G1m17,1 (CH1 K120 (218) (122-219), hinge 1-15 (220-234), CH2 (235-344), CH3 D12 (360), L14 (362) (345-449), CHS (450-451)) (122-451)], (224-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV1-16*01 (86.3%) -IGKJ2*02 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (230-230'':233-233'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-DG44 cell line, glycoform alfa
Структура
Иностранные названия
- Zamerovimabum (латинское)
- Zamerovimab (английское)
- Zamerovimab (немецкое)
- Zamérovimab (французское)
- Zamerovimab (испанское)
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