Зампилимаб

Rec. INN (наименование, зарегистрированное ВОЗ)

DB16381

2098280-42-1

immunoglobulin G4-kappa, anti-[Homo sapiens TGM2 (transglutaminase 2, transglutaminase-2 (TG2), proteinglutamine-gamma-glutamyltransferase C polypeptide, TGC)], humanized and chimeric monoclonal antibody;
gamma4 heavy chain (1-441) [humanized VH (Homo sapiens IGHV3-23*03 (89.8%) -(IGHD) -IGHJ4*01 (100%)) [8.8.7] (1-114) -Homo sapiens IGHG4*01 (CH1 (115-212), hinge S10>P (222) (213-224), CH2 (225-334), CH3 (335- 439), CHS (440-441)) (115-441)], (128-214')-disulfide with kappa light chain chimeric (1'-214') [V-KAPPA (Mus muculus IGKV14-111*01 (82.1%)/Homo sapiens IGKV1- 16*01 (78.9%) -Homo sapiens IGKJ1*01 (91.7%)) [6.3.9] (1'-107') -Homo sapiens IGKC*01, Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (220-220":223-223")- bisdisulfide

Поделиться этой страницей