Зелдесмеран

Rec. INN (наименование, зарегистрированное ВОЗ)

2726459-47-6

messenger RNA (mRNA), 5'-capped, encoding a full-length, codon-optimised version of the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) spike (S) glycoprotein (based upon GenBank ID: MT270101.1), containing the D614G mutation, flanked by a 5' untranslated region (5'UTR) derived from the 5'UTR of tobacco etch virus and a 3' untranslated region (3'UTR) derived from the 3'UTR of Xenopus laevis beta globin mRNA, and terminated with a 3' polyadenylation (polyA) tail; contains N¹-methylpseudouridine instead of uridine (all-U>m¹Ψ).

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