Зиклумеран

Rec. INN (наименование, зарегистрированное ВОЗ)

2305431-29-0

messenger RNA (mRNA), 5' capped, encoding codon-optimised clustered regularly interspaced short palindromic repeats (CRISPR) associated protein 9 (Cas9), flanked by untranslated regions (UTR) with significant sequence homology to the Xenopus beta globin gene, and terminated with a polyadenylation (polyA) tail. A Kozak sequence precedes the open reading frame and the 5' cap is a synthetic anti-reverse cap analogue (ARCA); contains N¹- methylpseudouridine instead of uridine (all-U>m¹Ψ).

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