Зигакибарт
ZigakibartМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2642175-46-8
Химическое название
immunoglobulin G4-kappa, anti-[Homo sapiens TNFSF13 (tumor necrosis factor (TNF) superfamily member 13, APRIL, CD256)], humanized monoclonal antibody;
gamma4 heavy chain humanized (1-448) [VH humanized (Homo sapiens IGHV1-3*01 (83,7%) -(IGHD) -IGHJ4*01 (84,6%), CDR-IMGT [8.8.14] (26-33.51-58.97-110)) (1-121) -Homo sapiens IGHG4*01, G4v5 h P10, nG4m(a) CH2 L92 (CH1 (122-219), hinge 1-12 S10>P (229) (220-231), CH2 L92 (310) (232-341), CH3 (342-446), CHS (447-448)) (122-448)], (135-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA Homo sapiens IGKV1-5*01 (84%) -IGKJ2*02 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (227-227'':230-230'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DG44, glycoform alfa
gamma4 heavy chain humanized (1-448) [VH humanized (Homo sapiens IGHV1-3*01 (83,7%) -(IGHD) -IGHJ4*01 (84,6%), CDR-IMGT [8.8.14] (26-33.51-58.97-110)) (1-121) -Homo sapiens IGHG4*01, G4v5 h P10, nG4m(a) CH2 L92 (CH1 (122-219), hinge 1-12 S10>P (229) (220-231), CH2 L92 (310) (232-341), CH3 (342-446), CHS (447-448)) (122-448)], (135-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA Homo sapiens IGKV1-5*01 (84%) -IGKJ2*02 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (227-227'':230-230'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DG44, glycoform alfa
Структура
Иностранные названия
- Zigakibartum (латинское)
- Zigakibart (английское)
- Zigakibart (немецкое)
- Zigakibart (французское)
- Zigakibart (испанское)
Подробнее по теме
Узнайте дополнительные сведения о действующем веществе Зигакибарт: