Зилебесиран

Zilebesiran

МНН

Rec. INN (наименование, зарегистрированное ВОЗ)

CAS

2380166-33-4

Химическое название

[(2S,4R)-1-{1-[(2-acetamido-2-deoxy-β-Dgalactopyranosyl)oxy]-16,16-bis({3-[(3-{5-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy]pentanamido}propyl)amino]-3-oxopropoxy}methyl)-5,11,18-trioxo-14-oxa-6,10,17- triazanonacosan-29-oyl}-4-hydroxypyrrolidin-2-yl]methyl all-P-ambo-2'-O-methyl-P-thioguanylyl-(3'→5')-2'-O-methyl-P-thiouridylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-deoxy-2'-fluorocytidylyl-(3'→5')-2'-O-methyladenylyl- (3'→5')-2'-deoxy-2'-fluorocytidylyl-(3'→5')-2'-deoxy-2'- fluoroadenylyl-(3'→5')-2'-deoxy-2'-fluoroadenylyl- (3'→5')-2'-O-methyluridylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-O-methyluridylyl- (3'→5')-2'-O-methyladenylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methyl-3'-adenylate, duplex with all-P-ambo-2'-O-methyl-P-thioadenylyl- (5'→3')-2'-O-methyl-P-thioguanylyl-(5'→3')-2'-O-methylcytidylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-O-methyluridylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-deoxy-2'-fluoroguanylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-deoxy-2'- fluorouridylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-O-methyluridylyl-(5'→3')-2'-O-methyluridylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-O-methylcytidylyl-(5'→3')-2'-O-methyluridylyl-(5'→3')-2'-O-methylcytidylyl-(5'→2')-1-de-β-D-ribofuranosyl-1-[(2S)-2,3-dihydroxypropyl]-5-methyluridylyl-(3'→3')-2'-O-methylcytidylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-O-methyl-P-thiouridylyl-(5'→3')-2'-deoxy-2'-fluoro-P-thioguanylyl-(5'→3')-2'-O-methyluridine

Химическая формула

C532H721F7N177O321P43S6

Структура

Структура Зилебесиран

Иностранные названия

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