Зинлирвимаб
ZinlirvimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2417213-75-1
Химическое название
immunoglobulin G1-lambda2, anti-[human immunodeficiency virus type 1 (HIV-1) gp120 envelope glycoprotein N-glycan V3 region], Homo sapiens monoclonal antibody;
gamma1 heavy chain Homo sapiens (1-461) [VH (Homo sapiens IGHV4-4*08 (79.2%) -(IGHD) -IGHJ6*04 (85.0%), CDR-IMGT [8.7.26] (26-33.51-57.96-121)) (1-132) -Homo sapiens IGHG1*01, G1m17,1, G1v24 CH3 L107, S114 (CH1 K120 (229) (133-230), hinge 1-15 (231-245), CH2 (246-355), CH3 D12 (371), L14 (373), M107>L (443), N114>S (449) (356-460), CHS K2>del (461)) (133-461)], (235-213')-disulfide with lambda2 light chain Homo sapiens (1'-214') [V-LAMBDA (Homo sapiens IGLV3-21*01 (64.9%) -IGLJ2*01 (80.0%) G121>A (102), K123>R (104), CDR-IMGT [6.3.12] (22-27.45-47.87-98)) (1'-108') -Homo sapiens IGLC2*01 (100%) (109'-214')]; dimer (241-241'':244-244'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV, glycoform alfa
gamma1 heavy chain Homo sapiens (1-461) [VH (Homo sapiens IGHV4-4*08 (79.2%) -(IGHD) -IGHJ6*04 (85.0%), CDR-IMGT [8.7.26] (26-33.51-57.96-121)) (1-132) -Homo sapiens IGHG1*01, G1m17,1, G1v24 CH3 L107, S114 (CH1 K120 (229) (133-230), hinge 1-15 (231-245), CH2 (246-355), CH3 D12 (371), L14 (373), M107>L (443), N114>S (449) (356-460), CHS K2>del (461)) (133-461)], (235-213')-disulfide with lambda2 light chain Homo sapiens (1'-214') [V-LAMBDA (Homo sapiens IGLV3-21*01 (64.9%) -IGLJ2*01 (80.0%) G121>A (102), K123>R (104), CDR-IMGT [6.3.12] (22-27.45-47.87-98)) (1'-108') -Homo sapiens IGLC2*01 (100%) (109'-214')]; dimer (241-241'':244-244'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV, glycoform alfa
Структура
Иностранные названия
- Zinlirvimabum (латинское)
- Zinlirvimab (английское)
- Zinlirvimab (немецкое)
- Zinlirvimab (французское)
- Zinlirvimab (испанское)
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