Аксатилимаб

Rec. INN (наименование, зарегистрированное ВОЗ)

DB16388

N (не классифицировано FDA)

2155851-88-8

immunoglobulin G4-kappa, anti-[Homo sapiens CSF1R (colony stimulating factor 1 receptor, CSF-1R, CSF-1-R, macrophage colony-stimulating factor 1 receptor, c-fms, FMS, CD115)], humanized monoclonal antibody;
gamma4 heavy chain humanized (1-453) [VH (Homo sapiens IGHV2-70*11 (89.9%) -(IGHD) -IGHJ3*01 (92.9%)) [10.7.18] (1-126) -Homo sapiens IGHG4*01 (CH1 (127-224), hinge S10>P (234)(225-236), CH2 (237-346), CH3 (347-451), CHS (452-453)) (127-443)], (140-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV1-6*01 (87.2%) -IGKJ4*01 (100.0%)) [6.3.9] (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')];
dimer (232-232'':235-235'')-bisdisulfide, produced in Chinese Hamster Ovary (CHO) DG44 cell line, glycoform alfa

C₆₅₆₈H₁₀₀₉₂N₁₆₉₆O₂₀₅₂S₄₈

147185,68 г/моль

Поделиться этой страницей