Бамланивимаб

Rec. INN (наименование, зарегистрированное ВОЗ)

DB15718

N (не классифицировано FDA)

2423943-37-5

immunoglobulin G1-kappa, anti-[Homo sapiens severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein], Homo sapiens monoclonal antibody;
gamma1 heavy chain Homo sapiens (1-455) [VH (Homo sapiens IGHV1-69*04 (99.0%) -(IGHD) - IGHJ6*01 (90.9%) T123>A (120)) CDR-IMGT [8.8.18] (26-33.51-58.97-114) (1-125) -Homo sapiens IGHG1*03 (100%) G1m3, nG1m1 (CH1 R120 (222) (126-223), hinge 1-15 (224-238), CH2 (239-348), CH3 E12 (364), M14 (366) (349-453), CHS (454-455)) (126-454)], (228-214')-disulfide with kappa light chain Homo sapiens (1’-214’) [V-KAPPA (Homo sapiens IGKV1-39*01 (97.9%) -IGKJ1*01 (100%)) CDR-IMGT [6.3.9] (27-32.50-52.89-97) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (234-234":237-237")-bisdisulfide, produced in a Chinese hamster ovary (CHO) cell line derived from CHO-K1SV, lacking the Glutamine Synthetase (GS) gene, glycoform alfa

C₆₄₉₈H₁₀₀₆₈N₁₇₃₂O₂₀₃₂S₄₆

146000,0 Да

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