Деландистроген моксепарвовек
Delandistrogene moxeparvovecМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
Drugbank
DB16802
АТХ
Код МКБ 10
CAS
2305040-16-6
Химическое название
A non-replicating adeno-associated virus (AAV) vector encoding human micro-dystrophin.
A recombinant, non-replicating, adeno-associated virus (AAV) serotype rh74 vector (AAVrh74) encoding codon-optimized human micro-dystrophin (a shortened functional version of human dystrophin), under control of a hybrid MHCK7 promoter consisting of enhancer/promoter regions of murine muscle creatine kinase (CK) and alpha-myosin heavy-chain genes, followed by a chimeric intron [including the SV40 late 16S/19S splice signals and a small 5′ UTR] and a small synthetic polyadenylation (polyA) signal sequence, flanked by adeno-associated virus 2 (AAV2) inverted terminal repeats (ITRs).
A recombinant, non-replicating, adeno-associated virus (AAV) serotype rh74 vector (AAVrh74) encoding codon-optimized human micro-dystrophin (a shortened functional version of human dystrophin), under control of a hybrid MHCK7 promoter consisting of enhancer/promoter regions of murine muscle creatine kinase (CK) and alpha-myosin heavy-chain genes, followed by a chimeric intron [including the SV40 late 16S/19S splice signals and a small 5′ UTR] and a small synthetic polyadenylation (polyA) signal sequence, flanked by adeno-associated virus 2 (AAV2) inverted terminal repeats (ITRs).
Структура
Иностранные названия
- Delandistrogenum moxeparvovecum (латинское)
- Delandistrogene moxeparvovec (английское)
- Delandistrogen moxeparvovec (немецкое)
- Délandistrogène moxéparvovec (французское)
- Delandistrogén moxeparvovec (испанское)
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