Дивозилимаб
DivozilimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
АТХ
Фармакологическая группа
Код МКБ 10
Категория при беременности по FDA
N (не классифицировано FDA)
CAS
2254061-60-2
Химическое название
immunoglobulin G1-kappa, anti-[Homo sapiens MS4A1 (membrane-spanning 4-domains subfamily A member 1, CD20)], monoclonal antibody;
gamma1 heavy chain (1-451) [VH (Homo sapiens IGHV1-46*01 (86.7%) -(IGHD) -IGHJ1*01 (86.7%)) CDR-IMGT [8.8.14] (26-33.51-58.97-110) (1-121) -Homo sapiens IGHG1*03 (100%) G1m3, nG1m1 (CH1 R120 (218) (122-219), hinge 1-15 (220-234), CH2 (235-344), CH3 E12 (360), M14 (362) (345-449), CHS (450-451)) (122-451)], (224-213')-disulfide with kappa light chain (1'-213') [V-KAPPA (Mus musculus IGKV4-72*01 (85.3%) -IGKJ1*01 (90.9%)/Homo sapiens IGKV3D-11*02 (73.3%) -IGKJ4*01 (100%)) CDR-IMGT [5.3.9] (27-31.49-51.88-96) (1'-106') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (152), V101 (190) (107’-213’)]; dimer (230-230'':233-233'')-bisdisulfide, produced in a Chinese Hamster Ovary (CHO)-S cell line, glycoform alfa;
gamma1 heavy chain (1-451) [VH (Homo sapiens IGHV1-46*01 (86.7%) -(IGHD) -IGHJ1*01 (86.7%)) CDR-IMGT [8.8.14] (26-33.51-58.97-110) (1-121) -Homo sapiens IGHG1*03 (100%) G1m3, nG1m1 (CH1 R120 (218) (122-219), hinge 1-15 (220-234), CH2 (235-344), CH3 E12 (360), M14 (362) (345-449), CHS (450-451)) (122-451)], (224-213')-disulfide with kappa light chain (1'-213') [V-KAPPA (Mus musculus IGKV4-72*01 (85.3%) -IGKJ1*01 (90.9%)/Homo sapiens IGKV3D-11*02 (73.3%) -IGKJ4*01 (100%)) CDR-IMGT [5.3.9] (27-31.49-51.88-96) (1'-106') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (152), V101 (190) (107’-213’)]; dimer (230-230'':233-233'')-bisdisulfide, produced in a Chinese Hamster Ovary (CHO)-S cell line, glycoform alfa;
Структура
Иностранные названия
- Divozilimabum (латинское)
- Divozilimab (английское)
- Divozilimab (немецкое)
- Divozilimab (французское)
- Divozilimab (испанское)
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